L16V (p.Leu16Val) variant of CASP9 (Caspase-9)
L16V (p.Leu16Val) in CASP9 (Caspase-9) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.45 / 1. The record also includes population frequency data and structural context.
L16V (p.Leu16Val) variant details
- p.Leu16Val
- TOPMed rs1183397165
- gnomAD rs1183397165
- Missense
- Variant Prioritization Score for Impact Estimate 0.448
- REVEL 0.45
- CADD 23.90
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 1.8e-06)
- Structural context available