L106P (p.Leu106Pro) variant of CASP9 (Caspase-9)
L106P (p.Leu106Pro) in CASP9 (Caspase-9) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.20 / 1. The record also includes population frequency data and structural context.
L106P (p.Leu106Pro) variant details
- p.Leu106Pro
- ExAC rs745602740
- gnomAD rs745602740
- Missense
- Variant Prioritization Score for Impact Estimate 0.197
- REVEL 0.10
- CADD 17.10
- PolyPhen-2 0.64
- SIFT 0.17
- Most common in the REMAINING population (allele frequency 0.00048)
- Structural context available