I74V (p.Ile74Val) variant of CASP9 (Caspase-9)
I74V (p.Ile74Val) in CASP9 (Caspase-9) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.28 / 1. The record also includes population frequency data and structural context.
I74V (p.Ile74Val) variant details
- p.Ile74Val
- TOPMed rs1384265114
- gnomAD rs1384265114
- Missense
- Variant Prioritization Score for Impact Estimate 0.278
- REVEL 0.11
- CADD 20.60
- PolyPhen-2 0.40
- SIFT 0.38
- Most common in the Finnish in Finland (FIN) population (allele frequency 0.00091)
- Structural context available