I60V (p.Ile60Val) variant of CASP9 (Caspase-9)
I60V (p.Ile60Val) in CASP9 (Caspase-9) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.21 / 1. The record also includes population frequency data and structural context.
I60V (p.Ile60Val) variant details
- p.Ile60Val
- 1000Genomes rs200592766
- ExAC rs200592766
- TOPMed rs200592766
- gnomAD rs200592766
- Missense
- Variant Prioritization Score for Impact Estimate 0.214
- REVEL 0.06
- CADD 20.00
- PolyPhen-2 0.01
- SIFT 0.13
- Most common in the REMAINING population (allele frequency 0.00048)
- Structural context available