I60M (p.Ile60Met) variant of CASP9 (Caspase-9)
I60M (p.Ile60Met) in CASP9 (Caspase-9) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.11 / 1. The record also includes population frequency data and structural context.
I60M (p.Ile60Met) variant details
- p.Ile60Met
- gnomAD rs1429417115
- Missense
- Variant Prioritization Score for Impact Estimate 0.11
- REVEL 0.05
- CADD 17.60
- PolyPhen-2 0.23
- SIFT 0.12
- Most common in the African/African-American population (allele frequency 4.8e-05)
- Structural context available