I59T (p.Ile59Thr) variant of CASP9 (Caspase-9)
I59T (p.Ile59Thr) in CASP9 (Caspase-9) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.39 / 1. The record also includes population frequency data and structural context.
I59T (p.Ile59Thr) variant details
- p.Ile59Thr
- gnomAD rs1710040785
- Missense
- Variant Prioritization Score for Impact Estimate 0.393
- REVEL 0.23
- CADD 23.60
- Most common in the REMAINING population (allele frequency 0.00048)
- Structural context available