E41G (p.Glu41Gly) variant of CASP9 (Caspase-9)
E41G (p.Glu41Gly) in CASP9 (Caspase-9) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.47 / 1. The record also includes population frequency data and structural context.
E41G (p.Glu41Gly) variant details
- p.Glu41Gly
- Ensembl rs2103389631
- Missense
- Variant Prioritization Score for Impact Estimate 0.472
- REVEL 0.32
- CADD 32.00
- PolyPhen-2 0.91
- SIFT 0.02
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available