D79Y (p.Asp79Tyr) variant of CASP9 (Caspase-9)
D79Y (p.Asp79Tyr) in CASP9 (Caspase-9) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.55 / 1. The record also includes population frequency data and structural context.
D79Y (p.Asp79Tyr) variant details
- p.Asp79Tyr
- ExAC rs745486934
- TOPMed rs745486934
- gnomAD rs745486934
- Missense
- Variant Prioritization Score for Impact Estimate 0.551
- REVEL 0.37
- CADD 26.60
- PolyPhen-2 0.97
- SIFT 0.00
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available