D42G (p.Asp42Gly) variant of CASP9 (Caspase-9)
D42G (p.Asp42Gly) in CASP9 (Caspase-9) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.28 / 1. The record also includes population frequency data and structural context.
D42G (p.Asp42Gly) variant details
- p.Asp42Gly
- ExAC rs760750933
- TOPMed rs760750933
- gnomAD rs760750933
- Missense
- Variant Prioritization Score for Impact Estimate 0.282
- REVEL 0.12
- CADD 24.60
- PolyPhen-2 0.07
- SIFT 0.03
- Most common in the African/African-American population (allele frequency 4.8e-05)
- Structural context available