D23E (p.Asp23Glu) variant of CASP9 (Caspase-9)
D23E (p.Asp23Glu) in CASP9 (Caspase-9) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.03 / 1. The record also includes population frequency data and structural context.
D23E (p.Asp23Glu) variant details
- p.Asp23Glu
- ExAC rs763564932
- TOPMed rs763564932
- gnomAD rs763564932
- Missense
- Variant Prioritization Score for Impact Estimate 0.0348
- REVEL 0.00
- CADD 1.47
- PolyPhen-2 0.01
- SIFT 0.61
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available