C12F (p.Cys12Phe) variant of CASP9 (Caspase-9)
C12F (p.Cys12Phe) in CASP9 (Caspase-9) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.18 / 1. The record also includes population frequency data and structural context.
C12F (p.Cys12Phe) variant details
- p.Cys12Phe
- TOPMed rs1710342411
- Missense
- Variant Prioritization Score for Impact Estimate 0.176
- REVEL 0.04
- CADD 4.35
- PolyPhen-2 0.11
- SIFT 0.69
- Population evidence available
- Structural context available