Y29H (p.Tyr29His) variant of CASP8 (Caspase-8)
Y29H (p.Tyr29His) in CASP8 (Caspase-8) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.08 / 1. The record also includes population frequency data, published literature, and structural context.
Y29H (p.Tyr29His) variant details
- p.Tyr29His
- gnomAD 2-201266571-T-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.0781
- CADD 0.00
- PolyPhen-2 0.00
- SIFT 1.00
- Most common in the East Asian population (allele frequency 2.5e-05)
- Structural context available
- Literature evidence available