Y29C (p.Tyr29Cys) variant of CASP8 (Caspase-8)
Y29C (p.Tyr29Cys) in CASP8 (Caspase-8) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.47 / 1. The record also includes population frequency data and structural context.
Y29C (p.Tyr29Cys) variant details
- p.Tyr29Cys
- gnomAD rs1430228154
- Missense
- Variant Prioritization Score for Impact Estimate 0.472
- CADD 10.30
- PolyPhen-2 0.01
- SIFT 0.01
- Most common in the Non-Finnish European population (allele frequency 8.8e-05)
- Structural context available