S4T (p.Ser4Thr) variant of CASP8 (Caspase-8)
S4T (p.Ser4Thr) in CASP8 (Caspase-8) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.06 / 1. The record also includes population frequency data, published literature, and structural context.
S4T (p.Ser4Thr) variant details
- p.Ser4Thr
- gnomAD 2-201266497-G-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.0564
- CADD 0.03
- PolyPhen-2 0.00
- SIFT 0.29
- Most common in the Non-Finnish European population (allele frequency 1.8e-06)
- Structural context available
- Literature evidence available