S4S (p.Ser4Ser) variant of CASP8 (Caspase-8)
S4S (p.Ser4Ser) in CASP8 (Caspase-8) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.10 / 1. The record also includes population frequency data, published literature, and structural context.
S4S (p.Ser4Ser) variant details
- p.Ser4Ser
- gnomAD 2-201266498-C-T
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.0964
- CADD 2.23
- Most common in the Finnish in Finland (FIN) population (allele frequency 0.00019)
- Structural context available
- Literature evidence available