S26N (p.Ser26Asn) variant of CASP8 (Caspase-8)
S26N (p.Ser26Asn) in CASP8 (Caspase-8) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.58 / 1. The record also includes population frequency data, published literature, and structural context.
S26N (p.Ser26Asn) variant details
- p.Ser26Asn
- gnomAD 2-201266563-G-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.584
- CADD 22.60
- PolyPhen-2 0.90
- SIFT 0.02
- Population evidence available
- Structural context available
- Literature evidence available