S26A (p.Ser26Ala) variant of CASP8 (Caspase-8)
S26A (p.Ser26Ala) in CASP8 (Caspase-8) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.13 / 1. The record also includes population frequency data, published literature, and structural context.
S26A (p.Ser26Ala) variant details
- p.Ser26Ala
- gnomAD 2-201258346-T-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.126
- CADD 6.37
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available
- Literature evidence available