S21S (p.Ser21Ser) variant of CASP8 (Caspase-8)
S21S (p.Ser21Ser) in CASP8 (Caspase-8) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.31 / 1. The record also includes population frequency data, published literature, and structural context.
S21S (p.Ser21Ser) variant details
- p.Ser21Ser
- gnomAD 2-201266549-C-T
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.309
- CADD 8.42
- Most common in the HGDP:FRENCH population (allele frequency 0.019)
- Structural context available
- Literature evidence available