S16T (p.Ser16Thr) variant of CASP8 (Caspase-8)
S16T (p.Ser16Thr) in CASP8 (Caspase-8) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.59 / 1. The record also includes population frequency data, published literature, and structural context.
S16T (p.Ser16Thr) variant details
- p.Ser16Thr
- rs1219836548
- gnomAD 2-201258269-G-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.592
- CADD 21.50
- Most common in the REMAINING population (allele frequency 0.00048)
- Structural context available
- Literature evidence available