S16S (p.Ser16Ser) variant of CASP8 (Caspase-8)
S16S (p.Ser16Ser) in CASP8 (Caspase-8) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.42 / 1. The record also includes population frequency data, published literature, and structural context.
S16S (p.Ser16Ser) variant details
- p.Ser16Ser
- gnomAD 2-201258270-T-C
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.423
- CADD 8.68
- Most common in the Non-Finnish European population (allele frequency 2.9e-05)
- Structural context available
- Literature evidence available