S16G (p.Ser16Gly) variant of CASP8 (Caspase-8)
S16G (p.Ser16Gly) in CASP8 (Caspase-8) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.46 / 1. The record also includes population frequency data, published literature, and structural context.
S16G (p.Ser16Gly) variant details
- p.Ser16Gly
- gnomAD 2-201266532-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.463
- CADD 16.10
- PolyPhen-2 0.61
- SIFT 0.10
- Most common in the 1KG:CLM population (allele frequency 0.0053)
- Structural context available
- Literature evidence available