R5R (p.Arg5Arg) variant of CASP8 (Caspase-8)
R5R (p.Arg5Arg) in CASP8 (Caspase-8) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.10 / 1. The record also includes population frequency data, published literature, and structural context.
R5R (p.Arg5Arg) variant details
- p.Arg5Arg
- gnomAD 2-201258246-A-G
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.0957
- CADD 2.12
- Most common in the HGDP:MAKRANI population (allele frequency 0.023)
- Structural context available
- Literature evidence available