R33R (p.Arg33Arg) variant of CASP8 (Caspase-8)
R33R (p.Arg33Arg) in CASP8 (Caspase-8) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.10 / 1. The record also includes population frequency data, published literature, and structural context.
R33R (p.Arg33Arg) variant details
- p.Arg33Arg
- rs2125047617
- gnomAD 2-201258336-G-A
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.0957
- CADD 2.49
- Most common in the African/African-American population (allele frequency 0.00031)
- Structural context available
- Literature evidence available