Q46H (p.Gln46His) variant of CASP8 (Caspase-8)
Q46H (p.Gln46His) in CASP8 (Caspase-8) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.45 / 1. The record also includes population frequency data and structural context.
Q46H (p.Gln46His) variant details
- p.Gln46His
- ExAC rs752831902
- TOPMed rs752831902
- gnomAD rs752831902
- Missense
- Variant Prioritization Score for Impact Estimate 0.454
- CADD 23.30
- PolyPhen-2 0.86
- SIFT 0.01
- Most common in the Finnish in Finland (FIN) population (allele frequency 0.00091)
- Structural context available