Q35L (p.Gln35Leu) variant of CASP8 (Caspase-8)
Q35L (p.Gln35Leu) in CASP8 (Caspase-8) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.36 / 1. The record also includes population frequency data and structural context.
Q35L (p.Gln35Leu) variant details
- p.Gln35Leu
- gnomAD rs1402540575
- Missense
- Variant Prioritization Score for Impact Estimate 0.362
- CADD 17.10
- PolyPhen-2 0.04
- SIFT 1.00
- Most common in the African/African-American population (allele frequency 4.8e-05)
- Structural context available