Q35K (p.Gln35Lys) variant of CASP8 (Caspase-8)
Q35K (p.Gln35Lys) in CASP8 (Caspase-8) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.74 / 1. The record also includes population frequency data and structural context.
Q35K (p.Gln35Lys) variant details
- p.Gln35Lys
- TOPMed rs1344190376
- gnomAD rs1344190376
- Missense
- Variant Prioritization Score for Impact Estimate 0.744
- CADD 22.90
- PolyPhen-2 0.30
- SIFT 0.32
- Most common in the East Asian population (allele frequency 2.5e-05)
- Structural context available