P37T (p.Pro37Thr) variant of CASP8 (Caspase-8)
P37T (p.Pro37Thr) in CASP8 (Caspase-8) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.31 / 1. The record also includes population frequency data, published literature, and structural context.
P37T (p.Pro37Thr) variant details
- p.Pro37Thr
- rs1947138527
- gnomAD 2-201258364-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.313
- CADD 19.10
- Most common in the African/African-American population (allele frequency 4.8e-05)
- Structural context available
- Literature evidence available