P37Q (p.Pro37Gln) variant of CASP8 (Caspase-8)
P37Q (p.Pro37Gln) in CASP8 (Caspase-8) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.17 / 1. The record also includes population frequency data, published literature, and structural context.
P37Q (p.Pro37Gln) variant details
- p.Pro37Gln
- rs753962983
- gnomAD 2-201258365-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.175
- CADD 13.30
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available
- Literature evidence available