P31T (p.Pro31Thr) variant of CASP8 (Caspase-8)
P31T (p.Pro31Thr) in CASP8 (Caspase-8) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.37 / 1. The record also includes population frequency data, published literature, and structural context.
P31T (p.Pro31Thr) variant details
- p.Pro31Thr
- gnomAD 2-201258298-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.366
- CADD 19.70
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available
- Literature evidence available