L27L (p.Leu27Leu) variant of CASP8 (Caspase-8)
L27L (p.Leu27Leu) in CASP8 (Caspase-8) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.32 / 1. The record also includes population frequency data, published literature, and structural context.
L27L (p.Leu27Leu) variant details
- p.Leu27Leu
- gnomAD 2-201266567-G-A
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.317
- CADD 5.98
- Most common in the African/African-American population (allele frequency 4.8e-05)
- Structural context available
- Literature evidence available