L19P (p.Leu19Pro) variant of CASP8 (Caspase-8)
L19P (p.Leu19Pro) in CASP8 (Caspase-8) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.63 / 1. The record also includes population frequency data and structural context.
L19P (p.Leu19Pro) variant details
- p.Leu19Pro
- TOPMed rs1477942244
- gnomAD rs1477942244
- Missense
- Variant Prioritization Score for Impact Estimate 0.632
- CADD 25.40
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available