K39E (p.Lys39Glu) variant of CASP8 (Caspase-8)
K39E (p.Lys39Glu) in CASP8 (Caspase-8) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.08 / 1. The record also includes population frequency data, published literature, and structural context.
K39E (p.Lys39Glu) variant details
- p.Lys39Glu
- gnomAD 2-201266601-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.0812
- CADD 3.37
- PolyPhen-2 0.03
- SIFT 0.22
- Most common in the Finnish in Finland (FIN) population (allele frequency 0.00091)
- Structural context available
- Literature evidence available