K34T (p.Lys34Thr) variant of CASP8 (Caspase-8)
K34T (p.Lys34Thr) in CASP8 (Caspase-8) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.43 / 1. The record also includes population frequency data, published literature, and structural context.
K34T (p.Lys34Thr) variant details
- p.Lys34Thr
- gnomAD 2-201266587-A-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.434
- CADD 25.20
- PolyPhen-2 0.98
- SIFT 0.00
- Population evidence available
- Structural context available
- Literature evidence available