K23I (p.Lys23Ile) variant of CASP8 (Caspase-8)
K23I (p.Lys23Ile) in CASP8 (Caspase-8) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.68 / 1. The record also includes population frequency data, published literature, and structural context.
K23I (p.Lys23Ile) variant details
- p.Lys23Ile
- rs3769823
- gnomAD 2-201258272-A-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.681
- CADD 22.20
- Population evidence available
- Structural context available
- Cited in: A genome-wide cross-cancer meta-analysis highlights the shared genetic links of five solid cancers. (PMID 36819030)
- Cited in: Immunogenetic Determinants of Susceptibility to Head and Neck Cancer in the Million Veteran Program Cohort. (PMID 36378845)