I10S (p.Ile10Ser) variant of CASP8 (Caspase-8)
I10S (p.Ile10Ser) in CASP8 (Caspase-8) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.12 / 1. The record also includes population frequency data, published literature, and structural context.
I10S (p.Ile10Ser) variant details
- p.Ile10Ser
- gnomAD 2-201258263-T-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.116
- CADD 5.00
- Most common in the Middle Eastern population (allele frequency 0.0007)
- Structural context available
- Literature evidence available