G11T (p.Gly11Thr) variant of CASP8 (Caspase-8)
G11T (p.Gly11Thr) in CASP8 (Caspase-8) is a protein-truncating change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.19 / 1. The record also includes population frequency data, published literature, and structural context.
G11T (p.Gly11Thr) variant details
- p.Gly11Thr
- rs777586802
- gnomAD 2-201258276-A-AAA
- Frameshift
- Variant Prioritization Score for Impact Estimate 0.188
- CADD 15.10
- Most common in the 1KG:MSL population (allele frequency 0.013)
- Structural context available
- Literature evidence available