G11D (p.Gly11Asp) variant of CASP8 (Caspase-8)
G11D (p.Gly11Asp) in CASP8 (Caspase-8) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.26 / 1. The record also includes population frequency data, published literature, and structural context.
G11D (p.Gly11Asp) variant details
- p.Gly11Asp
- rs1947123947
- gnomAD 2-201258242-G-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.26
- CADD 9.54
- Most common in the 1KG:MSL population (allele frequency 0.013)
- Structural context available
- Literature evidence available