G11C (p.Gly11Cys) variant of CASP8 (Caspase-8)
G11C (p.Gly11Cys) in CASP8 (Caspase-8) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.27 / 1. The record also includes population frequency data, published literature, and structural context.
G11C (p.Gly11Cys) variant details
- p.Gly11Cys
- gnomAD 2-201258373-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.266
- CADD 16.20
- Most common in the REMAINING population (allele frequency 0.00048)
- Structural context available
- Literature evidence available