F24I (p.Phe24Ile) variant of CASP8 (Caspase-8)
F24I (p.Phe24Ile) in CASP8 (Caspase-8) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.12 / 1. The record also includes population frequency data, published literature, and structural context.
F24I (p.Phe24Ile) variant details
- p.Phe24Ile
- rs1286373288
- gnomAD 2-201258295-T-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.118
- CADD 5.29
- Most common in the Middle Eastern population (allele frequency 0.0007)
- Structural context available
- Literature evidence available