D28D (p.Asp28Asp) variant of CASP8 (Caspase-8)
D28D (p.Asp28Asp) in CASP8 (Caspase-8) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.09 / 1. The record also includes population frequency data, published literature, and structural context.
D28D (p.Asp28Asp) variant details
- p.Asp28Asp
- rs368413113
- gnomAD 2-201266570-C-T
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.0859
- CADD 0.74
- Most common in the African/African-American population (allele frequency 0.00012)
- Structural context available
- Literature evidence available