D15G (p.Asp15Gly) variant of CASP8 (Caspase-8)
D15G (p.Asp15Gly) in CASP8 (Caspase-8) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.06 / 1. The record also includes population frequency data, published literature, and structural context.
D15G (p.Asp15Gly) variant details
- p.Asp15Gly
- gnomAD 2-201266530-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.0636
- CADD 0.04
- PolyPhen-2 0.04
- SIFT 0.50
- Most common in the HGDP:BURUSHO population (allele frequency 0.042)
- Structural context available
- Literature evidence available