A41G (p.Ala41Gly) variant of CASP8 (Caspase-8)
A41G (p.Ala41Gly) in CASP8 (Caspase-8) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.59 / 1. The record also includes population frequency data and structural context.
A41G (p.Ala41Gly) variant details
- p.Ala41Gly
- TOPMed rs1356214774
- Missense
- Variant Prioritization Score for Impact Estimate 0.593
- CADD 22.60
- PolyPhen-2 0.56
- SIFT 0.27
- Most common in the East Asian population (allele frequency 0.00015)
- Structural context available