A41A (p.Ala41Ala) variant of CASP8 (Caspase-8)
A41A (p.Ala41Ala) in CASP8 (Caspase-8) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.66 / 1. The record also includes population frequency data, published literature, and structural context.
A41A (p.Ala41Ala) variant details
- p.Ala41Ala
- gnomAD 2-201258357-G-A
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.661
- CADD 9.67
- Most common in the African/African-American population (allele frequency 4.8e-05)
- Structural context available
- Literature evidence available