A20D (p.Ala20Asp) variant of CASP8 (Caspase-8)
A20D (p.Ala20Asp) in CASP8 (Caspase-8) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.19 / 1. The record also includes population frequency data, published literature, and structural context.
A20D (p.Ala20Asp) variant details
- p.Ala20Asp
- rs1489060781
- gnomAD 2-201258293-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.188
- CADD 15.10
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available
- Literature evidence available