Y83C (p.Tyr83Cys) variant of CASP3 (Caspase-3)
Y83C (p.Tyr83Cys) in CASP3 (Caspase-3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.58 / 1. The record also includes population frequency data and structural context.
Y83C (p.Tyr83Cys) variant details
- p.Tyr83Cys
- ExAC rs749985298
- gnomAD rs749985298
- Missense
- Variant Prioritization Score for Impact Estimate 0.583
- REVEL 0.53
- CADD 28.10
- PolyPhen-2 0.99
- SIFT 0.00
- Most common in the East Asian population (allele frequency 0.00015)
- Structural context available