V69I (p.Val69Ile) variant of CASP3 (Caspase-3)
V69I (p.Val69Ile) in CASP3 (Caspase-3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.25 / 1. The record also includes population frequency data and structural context.
V69I (p.Val69Ile) variant details
- p.Val69Ile
- ExAC rs754598802
- gnomAD rs754598802
- Missense
- Variant Prioritization Score for Impact Estimate 0.252
- REVEL 0.03
- CADD 20.70
- PolyPhen-2 0.08
- SIFT 0.09
- Most common in the HGDP:MAKRANI population (allele frequency 0.023)
- Structural context available