V117M (p.Val117Met) variant of CASP3 (Caspase-3)
V117M (p.Val117Met) in CASP3 (Caspase-3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.42 / 1. The record also includes population frequency data, published literature, and structural context.
V117M (p.Val117Met) variant details
- p.Val117Met
- gnomAD 4-184631899-C-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.419
- REVEL 0.33
- CADD 23.40
- PolyPhen-2 0.99
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 2.9e-05)
- Structural context available
- Literature evidence available