V117G (p.Val117Gly) variant of CASP3 (Caspase-3)
V117G (p.Val117Gly) in CASP3 (Caspase-3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.55 / 1. The record also includes population frequency data and structural context.
V117G (p.Val117Gly) variant details
- p.Val117Gly
- 1000Genomes rs78678473
- ESP rs78678473
- ExAC rs78678473
- TOPMed rs78678473
- Missense
- Variant Prioritization Score for Impact Estimate 0.546
- REVEL 0.48
- CADD 26.10
- PolyPhen-2 0.98
- SIFT 0.03
- Most common in the African/African-American population (allele frequency 0.00031)
- Structural context available