V115I (p.Val115Ile) variant of CASP3 (Caspase-3)
V115I (p.Val115Ile) in CASP3 (Caspase-3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.13 / 1. The record also includes population frequency data and structural context.
V115I (p.Val115Ile) variant details
- p.Val115Ile
- ESP rs371766825
- ExAC rs371766825
- TOPMed rs371766825
- gnomAD rs371766825
- Missense
- Variant Prioritization Score for Impact Estimate 0.132
- REVEL 0.12
- CADD 11.50
- PolyPhen-2 0.17
- SIFT 0.32
- Most common in the REMAINING population (allele frequency 0.00048)
- Structural context available