T62R (p.Thr62Arg) variant of CASP3 (Caspase-3)
T62R (p.Thr62Arg) in CASP3 (Caspase-3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.23 / 1. The record also includes population frequency data, published literature, and structural context.
T62R (p.Thr62Arg) variant details
- p.Thr62Arg
- gnomAD 4-184632390-G-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.225
- REVEL 0.10
- CADD 17.60
- PolyPhen-2 0.01
- SIFT 0.15
- Most common in the Finnish in Finland (FIN) population (allele frequency 0.00019)
- Structural context available
- Literature evidence available